{"id":347,"date":"2024-07-05T09:04:39","date_gmt":"2024-07-05T07:04:39","guid":{"rendered":"https:\/\/bcamonitor.org\/?p=347"},"modified":"2026-09-22T13:06:34","modified_gmt":"2026-09-22T13:06:34","slug":"new-eau-utuc-guidelines-2024-mention-urinary-biomarkers","status":"publish","type":"post","link":"https:\/\/bcamonitor.org\/?p=347","title":{"rendered":"NEW EAU UTUC guidelines 2024 mention urinary biomarkers"},"content":{"rendered":"<p>[et_pb_section fb_built=&#8221;1&#8243; _builder_version=&#8221;4.16&#8243; min_height=&#8221;392px&#8221; custom_margin=&#8221;||2px|||&#8221; custom_padding=&#8221;0px||0px|||&#8221; global_colors_info=&#8221;{}&#8221; theme_builder_area=&#8221;post_content&#8221;][et_pb_row _builder_version=&#8221;4.16&#8243; background_size=&#8221;initial&#8221; background_position=&#8221;top_left&#8221; background_repeat=&#8221;repeat&#8221; min_height=&#8221;372px&#8221; custom_padding=&#8221;||8px|||&#8221; global_colors_info=&#8221;{}&#8221; theme_builder_area=&#8221;post_content&#8221;][et_pb_column type=&#8221;4_4&#8243; _builder_version=&#8221;4.16&#8243; custom_padding=&#8221;|||&#8221; global_colors_info=&#8221;{}&#8221; custom_padding__hover=&#8221;|||&#8221; theme_builder_area=&#8221;post_content&#8221;][et_pb_text _builder_version=&#8221;4.16&#8243; header_text_color=&#8221;#3b8dbf&#8221; background_size=&#8221;initial&#8221; background_position=&#8221;top_left&#8221; background_repeat=&#8221;repeat&#8221; min_height=&#8221;382.6px&#8221; custom_margin=&#8221;-24px||||false|false&#8221; custom_padding=&#8221;0px||||false|false&#8221; global_colors_info=&#8221;{}&#8221; theme_builder_area=&#8221;post_content&#8221;]<\/p>\n<p><em><\/em><\/p>\n<p><em>\u00a0Reviewed by Marek Babjuk and Paolo Gontero<\/em><\/p>\n<p>&nbsp;<\/p>\n<p><strong>The 2024 EAU guidelines mention a study concluding that FISH and Bladder EpiCheck\u00ae along with cytology could be helpful as an ancillary tool in the diagnosis of upper tract urothelial carcinoma (UTUC) [1].<\/strong><\/p>\n<p>The standard recommended tools for the diagnosis of UTUC include computed tomography (CT) urography for diagnosis and staging and a urethrocystoscopy to rule out bladder tumour [1]. If imaging and voided urine cytology are not sufficient for the diagnosis and\/or risk-stratification of patients suspected to have UTUC, diagnostic ureteroscopy is recommended [1].<\/p>\n<p>Despite being the standard of care for UTUC diagnosis, CT urography cannot detect carcinoma in situ (CIS) and flat lesions, and endoscopic procedures are invasive and cumbersome [2,3].<\/p>\n<p><strong>A recent prospective study in 79 patients showed promising results of urine biomarker tests (Bladder EpiCheck\u00ae and Urovysion\u00ae-FISH) and concluded that these tests could be helpful ancillary methods for the detection of UTUC [4].<\/strong><\/p>\n<p><span>\u2192\u00a0<\/span><a href=\"https:\/\/bcamonitor.org\/2024\/02\/02\/the-diagnostic-value-of-urinary-biomarkers-in-utuc\/\" target=\"_blank\" rel=\"noopener noreferrer\">Read our update on this study here<\/a><\/p>\n<p>Despite these promising data, the low number of cases included in this study cannot allow any definitive conclusions and multicentric, randomised studies are needed.<\/p>\n<p>Consequently, the guidelines, other than appraising the diagnostic value of FISH and Bladder EpiCheck\u00ae along with cytology in the detection of UTUC, also state the need for well-designed prospective comparative trials to further confirm their diagnostic utility for UTUC.<\/p>\n<p>&nbsp;<\/p>\n<p>[\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=&#8221;1&#8243; _builder_version=&#8221;4.16&#8243; custom_margin=&#8221;||-6px|||&#8221; custom_padding=&#8221;0px||0px|||&#8221; locked=&#8221;off&#8221; global_colors_info=&#8221;{}&#8221; theme_builder_area=&#8221;post_content&#8221;][et_pb_row _builder_version=&#8221;4.16&#8243; background_size=&#8221;initial&#8221; background_position=&#8221;top_left&#8221; background_repeat=&#8221;repeat&#8221; custom_padding=&#8221;28px||0px|||&#8221; global_colors_info=&#8221;{}&#8221; theme_builder_area=&#8221;post_content&#8221;][et_pb_column type=&#8221;4_4&#8243; _builder_version=&#8221;4.16&#8243; custom_padding=&#8221;|||&#8221; global_colors_info=&#8221;{}&#8221; custom_padding__hover=&#8221;|||&#8221; theme_builder_area=&#8221;post_content&#8221;][et_pb_text disabled_on=&#8221;off|off|off&#8221; _builder_version=&#8221;4.16&#8243; header_text_color=&#8221;#3b8dbf&#8221; background_size=&#8221;initial&#8221; background_position=&#8221;top_left&#8221; background_repeat=&#8221;repeat&#8221; custom_margin=&#8221;45px|||||&#8221; custom_padding=&#8221;0px|||||&#8221; global_colors_info=&#8221;{}&#8221; theme_builder_area=&#8221;post_content&#8221;]<\/p>\n<h5><span style=\"text-decoration: underline\"><strong>Updated slide resource<\/strong><\/span><\/h5>\n<p><a href=\"https:\/\/bcamonitor.org\/2024\/02\/02\/the-diagnostic-value-of-urinary-biomarkers-in-utuc\/\"><\/a>We updated our comprehensive slide resource on biomarkers and included a new section on UTUC. Click on the button below to download the slide resource. Don\u2019t forget to share it with your colleagues as well!<\/p>\n<p>[\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row _builder_version=&#8221;4.16&#8243; global_colors_info=&#8221;{}&#8221; theme_builder_area=&#8221;post_content&#8221;][et_pb_column type=&#8221;4_4&#8243; _builder_version=&#8221;4.16&#8243; global_colors_info=&#8221;{}&#8221; theme_builder_area=&#8221;post_content&#8221;][et_pb_button button_url=&#8221;https:\/\/bcamonitor.org\/slides-brochure\/&#8221; url_new_window=&#8221;on&#8221; button_text=&#8221;Download the free slide resource and brochure&#8221; button_alignment=&#8221;center&#8221; _builder_version=&#8221;4.16&#8243; custom_button=&#8221;on&#8221; button_text_color=&#8221;#ffffff&#8221; button_bg_color=&#8221;#3b8dbf&#8221; button_border_width=&#8221;0px&#8221; global_colors_info=&#8221;{}&#8221; theme_builder_area=&#8221;post_content&#8221;][\/et_pb_button][et_pb_text _builder_version=&#8221;4.16&#8243; header_text_color=&#8221;#3b8dbf&#8221; background_size=&#8221;initial&#8221; background_position=&#8221;top_left&#8221; background_repeat=&#8221;repeat&#8221; custom_margin=&#8221;45px|||||&#8221; custom_padding=&#8221;0px|||||&#8221; global_colors_info=&#8221;{}&#8221; theme_builder_area=&#8221;post_content&#8221;]<\/p>\n<h5>[References]<\/h5>\n<ol>\n<ol>\n<li>Masson-Lecomte A, Gontero P, Birtle A, et al. European Association of Urology (EAU) guidelines on upper urinary tract urothelial carcinoma. Update April 2024. Available at: <a href=\"https:\/\/uroweb.org\/guidelines\/upper-urinary-tract-urothelial-cell-carcinoma\" target=\"_blank\" rel=\"noopener noreferrer\">https:\/\/uroweb.org\/guidelines\/upper-urinary-tract-urothelial-cell-carcinoma <\/a><\/li>\n<li>Coleman JA, Clark PE, Bixler BR, et al. Diagnosis and management of non-metastatic upper tract urothelial carcinoma: AUA\/SUO guideline. J Urol 2023;209:1071-81. Update April 2023. Available at: <a href=\"https:\/\/www.auanet.org\/guidelines-and-quality\/guidelines\/non-metastatic-upper-tract-urothelial-carcinoma\" target=\"_blank\" rel=\"noopener noreferrer\">https:\/\/www.auanet.org\/guidelines-and-quality\/guidelines\/non-metastatic-upper-tract-urothelial-carcinoma <\/a><\/li>\n<li>D\u2019Elia C, Trenti E, Krause P, et al. Ther Adv Urol 2022;doi: 10.1177\/17562872221090320. <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/35450126\/\" target=\"_blank\" rel=\"noopener noreferrer\">PubMed <\/a><\/li>\n<li>Pycha S, Trenti E, Mian C, et al. World J Urol 2023;41:1323-8. <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/36929411\/\" target=\"_blank\" rel=\"noopener noreferrer\">PubMed <\/a><\/li>\n<\/ol>\n<\/ol>\n<p>&nbsp;<\/p>\n<p>[\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=&#8221;1&#8243; _builder_version=&#8221;4.8.2&#8243; _module_preset=&#8221;default&#8221; custom_padding=&#8221;2px||5px|||&#8221; global_module=&#8221;303&#8243; saved_tabs=&#8221;all&#8221; global_colors_info=&#8221;{}&#8221; theme_builder_area=&#8221;post_content&#8221;][\/et_pb_section]<\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u00a0Reviewed by Marek Babjuk and Paolo Gontero &nbsp; The 2024 EAU guidelines mention a study concluding that FISH and Bladder EpiCheck\u00ae along with cytology could be helpful as an ancillary tool in the diagnosis of upper tract urothelial carcinoma (UTUC) [1]. The standard recommended tools for the diagnosis of UTUC include computed tomography (CT) urography [&hellip;]<\/p>\n","protected":false},"author":0,"featured_media":277,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_et_pb_use_builder":"on","_et_pb_old_content":"","_et_gb_content_width":"","footnotes":""},"categories":[9],"tags":[],"class_list":["post-347","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-publication"],"_links":{"self":[{"href":"https:\/\/bcamonitor.org\/index.php?rest_route=\/wp\/v2\/posts\/347","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/bcamonitor.org\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/bcamonitor.org\/index.php?rest_route=\/wp\/v2\/types\/post"}],"replies":[{"embeddable":true,"href":"https:\/\/bcamonitor.org\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=347"}],"version-history":[{"count":1,"href":"https:\/\/bcamonitor.org\/index.php?rest_route=\/wp\/v2\/posts\/347\/revisions"}],"predecessor-version":[{"id":363,"href":"https:\/\/bcamonitor.org\/index.php?rest_route=\/wp\/v2\/posts\/347\/revisions\/363"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/bcamonitor.org\/index.php?rest_route=\/wp\/v2\/media\/277"}],"wp:attachment":[{"href":"https:\/\/bcamonitor.org\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=347"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/bcamonitor.org\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=347"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/bcamonitor.org\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=347"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}